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Moreno J, Quintanilla JG, López-Farré A, Archondo T, Cervigón R, Aragoncillo P, Usandizaga E, Silva J, Rodríguez-Bobada C, Rojo JL, Pérez-Castellano N, Mironov S, Mont L, Pérez de Prada T, Macaya C, Pérez-Villacastín J

Skeletal myoblast implants induce minor propagation delays, but do not promote arrhythmias in the normal swine heart.

Europace. 2010 Nov;12(11):1637-44, PMID: 20675673

Whether skeletal myoblast (SM) implants are proarrhythmic is still controversial due to conflicting pre-clinical and clinical data. We hypothesized that if SM implants are arrhythmogenic, they will facilitate the induction of ventricular tachyarrhythmias by promoting heterogeneous propagation of activation wavefronts.

CARDIAC & CARDIOVASCULAR SYSTEMS

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