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Vivas D, Garcia-Rubira JC, Bernardo E, Angiolillo DJ, Martín P, Calle-Pascual A, Nuñez-Gil I, Macaya C, Fernández-Ortiz A

Effects of intensive glucose control on platelet reactivity in patients with acute coronary syndromes. Results of the CHIPS Study ("Control de Hiperglucemia y Actividad Plaquetaria en Pacientes con Sindrome Coronario Agudo").

Heart. 2011 May;97(10):803-9, PMID: 21378389

Hyperglycaemia has been associated with increased platelet reactivity and impaired prognosis in patients with acute coronary syndrome (ACS). Whether platelet reactivity can be reduced by lowering glucose in this setting is unknown. The aim of this study was to assess the functional impact of intensive glucose control with insulin on platelet reactivity in patients admitted with ACS and hyperglycaemia.


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