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Lluís-Ganella C, Lucas G, Subirana I, Sentí M, Jiménez-Conde J, Marrugat J, Tomás M, Elosua R

Additive effect of multiple genetic variants on the risk of coronary artery disease.

Rev Esp Cardiol. 2010 Aug;63(8):925-33, PMID: 20738937

Coronary artery disease (CAD) has a substantial genetic component and, in recent years, a number of genetic variants associated with the disease have been identified. The objective of this study was to evaluate the magnitude of the association between a genetic risk score, which is based on the accumulated number of risk alleles in all genetic variants of interest, and the presence of CAD.

CARDIAC & CARDIOVASCULAR SYSTEMS

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Ministerio de Economía y Competitividad Fondo Europeo de Desarrollo Regional IMIM - Parc de Salut Mar