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Diaz-Ricart M, Palomo M, Fusté B, Lopez-Vilchez I, Carbó C, Pérez-Pujol S, White JG, Escolar G

Inhibition of tyrosine kinase activity prevents the adhesive and cohesive properties of platelets and the expression of procoagulant activity in response to collagen.

Thromb. Res.. 2008;121(6):873-83, PMID: 17904203

Platelet activation leads to signal transduction mechanisms, in which phosphotyrosine proteins play a relevant role.

HEMATOLOGY