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Josa M, Castellà M, Paré C, Bedini JL, Cartañá R, Mestres CA, Pomar JL, Mulet J

Hemolysis in mechanical bileaflet prostheses: experience with the Bicarbon valve.

Ann. Thorac. Surg.. 2006 Apr;81(4):1291-6, PMID: 16564260

Normal functioning mechanical heart valve prostheses are designed to have a certain degree of intrinsic structural regurgitation as a washout mechanism to avoid prosthetic thrombosis. However, intrinsic regurgitation leads to blood cell trauma and hemolysis. Information on hemolysis associated with mechanical bileaflet prostheses is scarce. This study evaluated factors influencing hemolysis in 197 Bicarbon mechanical bileaflet prostheses implanted in 164 patients.

CARDIAC & CARDIOVASCULAR SYSTEMS