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Sinisalo J, Vlachopoulou E, Marchesani M, Nokelainen J, Mäyränpää MI, Lappalainen J, Paakkanen R, Wennerström A, Salli K, Niemi HJ, Männistö S, Salo P, Junttila J, Eskola M, Nikus K, Arstila TP, Perola M, Huikuri H, Karhunen PJ, Kovanen PT, Palotie A, Havulinna AS, Lluís-Ganella C, Marrugat J, Elosua R, Salomaa V, Nieminen MS, Lokki ML

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome.

Circ Cardiovasc Genet. 2016 Feb;9(1):55-63, PMID: 26679868

The HLA-DRB1*01 allele of the human leukocyte antigen has been associated with acute coronary syndrome. Genome-wide association studies have revealed associations with human leukocyte antigen and non-human leukocyte antigen genes of 3 major histocompatibility complex gene classes but not at allelic level.

GENETICS & HEREDITY

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