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Cidad P, Novensá L, Garabito M, Batlle M, Dantas AP, Heras M, López-López JR, Pérez-García MT, Roqué M

K+ channels expression in hypertension after arterial injury, and effect of selective Kv1.3 blockade with PAP-1 on intimal hyperplasia formation.

Cardiovasc Drugs Ther. 2014 Dec;28(6):501-11, PMID: 25348824

K(+) channels are central to vascular pathophysiology. Previous results demonstrated that phenotypic modulation associates with a change in Kv1.3 to Kv1.5 expression, and that Kv1.3 blockade inhibits proliferation of VSMCs cultures.


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